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Drug Discovery
Drug Discovery
Mycobacterium tuberculosis interactome analysis unravels potential pathways to drug resistance
Drug Discovery / Biological Sciences / Tuberculosis / Mycobacterium tuberculosis / Drug Resistance / Shortest Path / Drug Targeting / Drug treatment / Shortest Path / Drug Targeting / Drug treatment
Adamantyl Analogues of Paracetamol as Potent Analgesic Drugs via Inhibition of TRPA1
Chemistry / Medicinal Chemistry / Pain / Drug Discovery / Ion Channels / TRPV1 / Ibuprofen / Acetaminophen / Trpa1 / TRPV1 / Ibuprofen / Acetaminophen / Trpa1
Epiparasitic plants specialized on arbuscular mycorrhizal fungi
Pharmacology / Biochemistry / Bioinformatics / Evolutionary Biology / Genetics / Marine Biology / Neuroscience / Environmental Science / Geophysics / Physics / Materials Science / Quantum Physics / Developmental Biology / Immunology / Climate Change / Molecular Biology / Structural Biology / Genomics / RNA / Computational Biology / Transcriptomics / Carbon / Photosynthesis / Biotechnology / Systems Biology / Cancer / Symbiosis / Biology / Metabolomics / Cell Cycle / Proteomics / Argentina / Ecology / Drug Discovery / Evolution / Fungi / Nanotechnology / Astrophysics / Neurobiology / Medicine / Multidisciplinary / Palaeobiology / Functional Genomics / Nature / Signal Transduction / Astronomy / DNA / Phylogeny / Arbuscular mycorrhizal fungi / Cell Signalling / Medical Research / Plants / Ectomycorrhizal fungi / Biological evolution / Microorganism / Mycorrhizal Fungi / Simbiosis / Heterotrophy / Vascular Plants / Earth Science / Thallophyta / Marine Biology / Neuroscience / Environmental Science / Geophysics / Physics / Materials Science / Quantum Physics / Developmental Biology / Immunology / Climate Change / Molecular Biology / Structural Biology / Genomics / RNA / Computational Biology / Transcriptomics / Carbon / Photosynthesis / Biotechnology / Systems Biology / Cancer / Symbiosis / Biology / Metabolomics / Cell Cycle / Proteomics / Argentina / Ecology / Drug Discovery / Evolution / Fungi / Nanotechnology / Astrophysics / Neurobiology / Medicine / Multidisciplinary / Palaeobiology / Functional Genomics / Nature / Signal Transduction / Astronomy / DNA / Phylogeny / Arbuscular mycorrhizal fungi / Cell Signalling / Medical Research / Plants / Ectomycorrhizal fungi / Biological evolution / Microorganism / Mycorrhizal Fungi / Simbiosis / Heterotrophy / Vascular Plants / Earth Science / Thallophyta
MicroRNA expression profiles classify human cancers
Pharmacology / Biochemistry / Bioinformatics / Evolutionary Biology / Genetics / Marine Biology / Neuroscience / Environmental Science / Geophysics / Physics / Materials Science / Quantum Physics / Developmental Biology / Immunology / Climate Change / Molecular Biology / Structural Biology / Genomics / RNA / Computational Biology / Transcriptomics / Biotechnology / Systems Biology / MicroRNA / Cancer / Flow Cytometry / Biology / Metabolomics / Cell Cycle / Proteomics / Ecology / Drug Discovery / Evolution / Nanotechnology / Astrophysics / Neurobiology / Medicine / Multidisciplinary / Palaeobiology / Functional Genomics / Nature / Signal Transduction / Non Coding Rna / Astronomy / DNA / Humans / Animals / Cancer Diagnosis / Cell Signalling / Medical Research / microRNAs / Neoplasms / Biological Process / Sensitivity and Specificity / Expression analysis / Earth Science / Gene expression profiling / Marine Biology / Neuroscience / Environmental Science / Geophysics / Physics / Materials Science / Quantum Physics / Developmental Biology / Immunology / Climate Change / Molecular Biology / Structural Biology / Genomics / RNA / Computational Biology / Transcriptomics / Biotechnology / Systems Biology / MicroRNA / Cancer / Flow Cytometry / Biology / Metabolomics / Cell Cycle / Proteomics / Ecology / Drug Discovery / Evolution / Nanotechnology / Astrophysics / Neurobiology / Medicine / Multidisciplinary / Palaeobiology / Functional Genomics / Nature / Signal Transduction / Non Coding Rna / Astronomy / DNA / Humans / Animals / Cancer Diagnosis / Cell Signalling / Medical Research / microRNAs / Neoplasms / Biological Process / Sensitivity and Specificity / Expression analysis / Earth Science / Gene expression profiling
Antiviral lead compounds from marine sponges
Biotechnology / Symbiosis / Drug Discovery / Metagenomics / Porifera / Herpes Simplex / Humans / Animals / Aquatic organisms / Marine Drugs / Antiviral Agents / Herpes Simplex / Humans / Animals / Aquatic organisms / Marine Drugs / Antiviral Agents
Epiparasitic plants specialized on arbuscular mycorrhizal fungi
Pharmacology / Biochemistry / Bioinformatics / Evolutionary Biology / Genetics / Marine Biology / Neuroscience / Environmental Science / Geophysics / Physics / Materials Science / Quantum Physics / Developmental Biology / Immunology / Climate Change / Molecular Biology / Structural Biology / Genomics / RNA / Computational Biology / Transcriptomics / Carbon / Photosynthesis / Biotechnology / Systems Biology / Cancer / Symbiosis / Biology / Metabolomics / Cell Cycle / Proteomics / Argentina / Ecology / Drug Discovery / Evolution / Fungi / Nanotechnology / Astrophysics / Neurobiology / Medicine / Multidisciplinary / Palaeobiology / Functional Genomics / Nature / Signal Transduction / Astronomy / DNA / Phylogeny / Arbuscular mycorrhizal fungi / Cell Signalling / Medical Research / Plants / Ectomycorrhizal fungi / Biological evolution / Microorganism / Mycorrhizal Fungi / Simbiosis / Heterotrophy / Vascular Plants / Earth Science / Thallophyta / Marine Biology / Neuroscience / Environmental Science / Geophysics / Physics / Materials Science / Quantum Physics / Developmental Biology / Immunology / Climate Change / Molecular Biology / Structural Biology / Genomics / RNA / Computational Biology / Transcriptomics / Carbon / Photosynthesis / Biotechnology / Systems Biology / Cancer / Symbiosis / Biology / Metabolomics / Cell Cycle / Proteomics / Argentina / Ecology / Drug Discovery / Evolution / Fungi / Nanotechnology / Astrophysics / Neurobiology / Medicine / Multidisciplinary / Palaeobiology / Functional Genomics / Nature / Signal Transduction / Astronomy / DNA / Phylogeny / Arbuscular mycorrhizal fungi / Cell Signalling / Medical Research / Plants / Ectomycorrhizal fungi / Biological evolution / Microorganism / Mycorrhizal Fungi / Simbiosis / Heterotrophy / Vascular Plants / Earth Science / Thallophyta
Discovery of novel 1H-imidazol-2-yl-pyrimidine-4,6-diamines as potential antimalarials
Organic Chemistry / Drug Discovery / Animals / Drug Resistance / Plasmodium falciparum / Antimalarials / Bioorganic and medicinal Chemistry / Structure activity Relationship / Antimalarials / Bioorganic and medicinal Chemistry / Structure activity Relationship
presas
Pharmacology / Neuroscience / Immunology / Molecular Medicine / Treatment / Drug Discovery / Biological Sciences / Humans / Cholesterol / Vaccination / Metabolic pathway / Brain Chemistry / Drug Targeting / Alzheimer Disease / Drug Discovery / Biological Sciences / Humans / Cholesterol / Vaccination / Metabolic pathway / Brain Chemistry / Drug Targeting / Alzheimer Disease
An estrogen receptor chimera senses ligands by nuclear translocation
Biochemistry / Fluorescence Microscopy / Drug Discovery / Fluorescent Dyes and Reagents / STEROIDS / High Content Screening / Estrogen Receptor / Cercopithecus aethiops / Dexamethasone / Cell line / Humans / Mice / Animals / Immunoprecipitation / Tamoxifen / Time Factors / Transfection / Protein Binding / Cytoplasm / Ligands / Glucocorticoids / Estradiol / Protein Transport / Biochemistry and cell biology / High Content Screening / Estrogen Receptor / Cercopithecus aethiops / Dexamethasone / Cell line / Humans / Mice / Animals / Immunoprecipitation / Tamoxifen / Time Factors / Transfection / Protein Binding / Cytoplasm / Ligands / Glucocorticoids / Estradiol / Protein Transport / Biochemistry and cell biology
Complementary medicinal chemistry‐driven strategies toward new antitrypanosomal and antileishmanial lead drug candidates
Immunology / Medical Microbiology / Treatment / Drug Discovery / Leishmania / Pharmaceutical Chemistry / Leishmaniasis / Humans / Animals / Lead / Drug Design / Complementary Medicine / Trypanosoma / Trypanosomiasis / Trypanocidal Agents / Quinazolines / Pharmaceutical Chemistry / Leishmaniasis / Humans / Animals / Lead / Drug Design / Complementary Medicine / Trypanosoma / Trypanosomiasis / Trypanocidal Agents / Quinazolines
Mitotic Occupancy and Lineage-Specific Transcriptional Control of RRNA Genes by Runx2
Pharmacology / Biochemistry / Bioinformatics / Evolutionary Biology / Genetics / Marine Biology / Neuroscience / Environmental Science / Geophysics / Physics / Materials Science / Quantum Physics / Developmental Biology / Immunology / Climate Change / Molecular Biology / Structural Biology / Genomics / RNA / Computational Biology / Transcriptomics / Biotechnology / Systems Biology / Cancer / Biology / Metabolomics / Cell Cycle / Proteomics / Ecology / Drug Discovery / Evolution / Regulation / Nanotechnology / RNA polymerase / Astrophysics / Neurobiology / Medicine / Multidisciplinary / Palaeobiology / Functional Genomics / Nature / Protein synthesis / Cell Division / Signal Transduction / Transcription / Astronomy / DNA / RNA interference / Mitosis / Cell line / Cell Differentiation / Humans / Mice / Animals / Histone Modification / Cell Signalling / Medical Research / Transcription Factor / ribosomal RNA / Multienzyme complexes / RNA Polymerase I / Cell Proliferation / Base Sequence / Cell Fate / Earth Science / Interphase / Marine Biology / Neuroscience / Environmental Science / Geophysics / Physics / Materials Science / Quantum Physics / Developmental Biology / Immunology / Climate Change / Molecular Biology / Structural Biology / Genomics / RNA / Computational Biology / Transcriptomics / Biotechnology / Systems Biology / Cancer / Biology / Metabolomics / Cell Cycle / Proteomics / Ecology / Drug Discovery / Evolution / Regulation / Nanotechnology / RNA polymerase / Astrophysics / Neurobiology / Medicine / Multidisciplinary / Palaeobiology / Functional Genomics / Nature / Protein synthesis / Cell Division / Signal Transduction / Transcription / Astronomy / DNA / RNA interference / Mitosis / Cell line / Cell Differentiation / Humans / Mice / Animals / Histone Modification / Cell Signalling / Medical Research / Transcription Factor / ribosomal RNA / Multienzyme complexes / RNA Polymerase I / Cell Proliferation / Base Sequence / Cell Fate / Earth Science / Interphase
Mitotic Occupancy and Lineage-Specific Transcriptional Control of RRNA Genes by Runx2
Pharmacology / Biochemistry / Bioinformatics / Evolutionary Biology / Genetics / Marine Biology / Neuroscience / Environmental Science / Geophysics / Physics / Materials Science / Quantum Physics / Developmental Biology / Immunology / Climate Change / Molecular Biology / Structural Biology / Genomics / RNA / Computational Biology / Transcriptomics / Biotechnology / Systems Biology / Cancer / Biology / Metabolomics / Cell Cycle / Proteomics / Ecology / Drug Discovery / Evolution / Regulation / Nanotechnology / RNA polymerase / Astrophysics / Neurobiology / Medicine / Multidisciplinary / Palaeobiology / Functional Genomics / Nature / Protein synthesis / Cell Division / Signal Transduction / Transcription / Astronomy / DNA / RNA interference / Mitosis / Cell line / Cell Differentiation / Humans / Mice / Animals / Histone Modification / Cell Signalling / Medical Research / Transcription Factor / ribosomal RNA / Multienzyme complexes / RNA Polymerase I / Cell Proliferation / Base Sequence / Cell Fate / Earth Science / Interphase / Marine Biology / Neuroscience / Environmental Science / Geophysics / Physics / Materials Science / Quantum Physics / Developmental Biology / Immunology / Climate Change / Molecular Biology / Structural Biology / Genomics / RNA / Computational Biology / Transcriptomics / Biotechnology / Systems Biology / Cancer / Biology / Metabolomics / Cell Cycle / Proteomics / Ecology / Drug Discovery / Evolution / Regulation / Nanotechnology / RNA polymerase / Astrophysics / Neurobiology / Medicine / Multidisciplinary / Palaeobiology / Functional Genomics / Nature / Protein synthesis / Cell Division / Signal Transduction / Transcription / Astronomy / DNA / RNA interference / Mitosis / Cell line / Cell Differentiation / Humans / Mice / Animals / Histone Modification / Cell Signalling / Medical Research / Transcription Factor / ribosomal RNA / Multienzyme complexes / RNA Polymerase I / Cell Proliferation / Base Sequence / Cell Fate / Earth Science / Interphase
Peroxisome-proliferator-activated receptor α agonists inhibit cyclo-oxygenase 2 and vascular endothelial growth factor transcriptional activation in human colorectal carcinoma cells via inhibition of activator protein-1
Molecular Biology / Gastroenterology / Drug Discovery / Biological Chemistry / Biological Sciences / Molecular and cellular biology / Hypertension / Fertility and Sterility / Biochemical / Clinical Sciences / CHEMICAL SCIENCES / Biochimie / Public health systems and services research / PPAR / Toll-Like Receptors Therapeutics Pharmacology / Neurosciences / Biochemistry and cell biology / Molecular and cellular biology / Hypertension / Fertility and Sterility / Biochemical / Clinical Sciences / CHEMICAL SCIENCES / Biochimie / Public health systems and services research / PPAR / Toll-Like Receptors Therapeutics Pharmacology / Neurosciences / Biochemistry and cell biology
Metagenomics: DNA sequencing of environmental samples
Pharmacology / Biochemistry / Bioinformatics / Evolutionary Biology / Genetics / Marine Biology / Neuroscience / Environmental Science / Geophysics / Physics / Materials Science / Quantum Physics / Developmental Biology / Immunology / Environmental microbiology / Climate Change / Molecular Biology / Structural Biology / Genomics / RNA / Computational Biology / Transcriptomics / Biotechnology / Systems Biology / Cancer / Biology / Metabolomics / Life Sciences / Cell Cycle / Proteomics / Ecology / Drug Discovery / Evolution / Nanotechnology / Astrophysics / Neurobiology / Medicine / Palaeobiology / Functional Genomics / Nature / Signal Transduction / Astronomy / DNA / Genetics & Microbial Biotechnology / Humans / Animals / Cell Signalling / Medical Research / Base Sequence / Earth Science / Lawrence Berkeley Laboratory / DNA sequence / Marine Biology / Neuroscience / Environmental Science / Geophysics / Physics / Materials Science / Quantum Physics / Developmental Biology / Immunology / Environmental microbiology / Climate Change / Molecular Biology / Structural Biology / Genomics / RNA / Computational Biology / Transcriptomics / Biotechnology / Systems Biology / Cancer / Biology / Metabolomics / Life Sciences / Cell Cycle / Proteomics / Ecology / Drug Discovery / Evolution / Nanotechnology / Astrophysics / Neurobiology / Medicine / Palaeobiology / Functional Genomics / Nature / Signal Transduction / Astronomy / DNA / Genetics & Microbial Biotechnology / Humans / Animals / Cell Signalling / Medical Research / Base Sequence / Earth Science / Lawrence Berkeley Laboratory / DNA sequence
Metagenomics: DNA sequencing of environmental samples
Pharmacology / Biochemistry / Bioinformatics / Evolutionary Biology / Genetics / Marine Biology / Neuroscience / Environmental Science / Geophysics / Physics / Materials Science / Quantum Physics / Developmental Biology / Immunology / Environmental microbiology / Climate Change / Molecular Biology / Structural Biology / Genomics / RNA / Computational Biology / Transcriptomics / Biotechnology / Systems Biology / Cancer / Biology / Metabolomics / Life Sciences / Cell Cycle / Proteomics / Ecology / Drug Discovery / Evolution / Nanotechnology / Astrophysics / Neurobiology / Medicine / Palaeobiology / Functional Genomics / Nature / Signal Transduction / Astronomy / DNA / Genetics & Microbial Biotechnology / Humans / Animals / Cell Signalling / Medical Research / Base Sequence / Earth Science / Lawrence Berkeley Laboratory / DNA sequence / Marine Biology / Neuroscience / Environmental Science / Geophysics / Physics / Materials Science / Quantum Physics / Developmental Biology / Immunology / Environmental microbiology / Climate Change / Molecular Biology / Structural Biology / Genomics / RNA / Computational Biology / Transcriptomics / Biotechnology / Systems Biology / Cancer / Biology / Metabolomics / Life Sciences / Cell Cycle / Proteomics / Ecology / Drug Discovery / Evolution / Nanotechnology / Astrophysics / Neurobiology / Medicine / Palaeobiology / Functional Genomics / Nature / Signal Transduction / Astronomy / DNA / Genetics & Microbial Biotechnology / Humans / Animals / Cell Signalling / Medical Research / Base Sequence / Earth Science / Lawrence Berkeley Laboratory / DNA sequence
Unusual antimalarial meroditerpenes from tropical red macroalgae
Organic Chemistry / Drug Discovery / Pharmacognosy / Structural Analysis / In Vitro / Humans / Circular Dichroism / Natural Product / Seaweed / Isolation / Absolute Configuration / Diterpenes / Plasmodium falciparum / Antimalarials / Conformational Analysis / Biological activity / Terpenoid / Humans / Circular Dichroism / Natural Product / Seaweed / Isolation / Absolute Configuration / Diterpenes / Plasmodium falciparum / Antimalarials / Conformational Analysis / Biological activity / Terpenoid
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